10 - AIIMS june 1999 microbiology mcqs

1q: which of the following is not seen in HIV patient with CD4 count less than 100 per microlitre , who has not productive cough ?

a. mycobacterium tuberculosis
b. pneumocystis carinii
c. mycoplasma pneumoniae
d. cryptococcal infection

answer c. mycoplasma pneumoniae

2q: risk of pneumococcal meningitis is seen in ?

a. post splenectomy patient
b. patient undergone neurosurgical intervention
c. patient following cardiac surgery
d. patient with hypoplasia of lung

answer a. post splenectomy patient

3q: which fungal infection is commonest to occur in neutropenia ?

a. candida
b. histoplasma
c. aspergillus niger
d. aspergillus fumigatus

answer a. candida

4q: all are true about rickettsia except ?

a. obligate intracellular
b. gram positive bacillus
c. arthropods are vectors
d. weil felix test is diagnostic

answer b. gram positive bacillus

5q: all are true about enterohaemorrhagic E.coli except ?

a. sereny test positive
b. may cause diarrhea
c. can cause hemolytic uremic syndrome
d. verocytotoxin is produced

answer a. sereny test positive

6q: all of the following are true regarding typhoid except ?

a. urinary carriers are more dangerous
b. Vi ab is used for detecting carrier
c. Vi is seen in normal population
d. Urine carrier is associated with anomalies

answer c. Vi is seen in normal population

9 - AIIMS november 2008 microbiology mcqs

63. biosaftey precaution grade iii is practiced in all except?

 
a. human influenza virus 
b. st louis encephalitis virus 
c. coxiella burnetti 
d. mycobacterium tuberculosis 

 answer: 

64. most common species of pseudomonas causing intravenous cathrter related infections? 

a. p. cepacia 
b. p.areuginosa 
c. p.maltiphila 
d. p.mallei

 answer:  

65. most sensitive diagnostic test for dengue is?

 a. Ig M elisa 
b. cft 
c. tissue culture 
d. electron microscopy 

answer:

66. a gardener has multiple vesicles on hand and multiple eruption s along the lymphatics. most common fungus responsible is?

a. sporothrix shenkii 
b. cladosporium 
c. histoplasma 
d. candida 

answer:

67. which is not a rna virus?

 a. ebola 
b. simian 40 
c. rabies 
d. vesicular stomatitis virus 

answer:

68. true about prion is? 

a. are virus coded 
b. cause misfolding of proteins 
c. cleave protein 
d. defect in folding of proteins 

answer:

69. all are true about bacteriophage except?

a. helps in transduction of bacteria 

b.  imparts toxigenicity to bacteria 

c. can transper chromosomal gene 

d.  

answer:

70: girl from shimla presented to opd with fever malaise and axillary and inguinal lymphadenopathy.culture shows stalactite growth.causative organism is? 

a. yersinia pestis 
b. francisella 
c. pseudomonas 

d.

answer: 

71.true about carbohydrate antigen are all except? 

a. has low immunogenicity 
b. memory response seen 
c. causes polyclonal b cell stimulation 
d. does not stimulate T cell

 answer:  

72.mechanism of action of pertusis toxin is? 

a. adp ribosylation 
b. 
c. 
d. acts through g alpha subunit 

answer:

 73.which of the following is true about isotypic variation? 

a. subtle amino acid changes due to allelic differences 
b. changes in aa heavy and light chain in variable region 
c. changes in heavy n light chain in constant region responsible for class and subtype 
d. these are areas in antigen that bind specifically to antibody 

answer:

74.true about hybridoma technique are all except ? 

a. narmal activated b cellsmyeloma cells 
b. myeloma cells selective mutation in salvage pathway, vigorous proliferation in hat medium 
c. thymidine kinase and hgprt catalyse he salvage pathway 
d. aminopterin a folic antagonist, inhibits de novo nucleotide synthesis 

 answer:

 to view all the 200 AIIMS november 2008 mcqs click here